RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
نویسندگان
چکیده
منابع مشابه
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure
RNA has the intrinsic property to base pair, forming complex structures fundamental to its diverse functions. Here, we develop PARIS, a method based on reversible psoralen crosslinking for global mapping of RNA duplexes with near base-pair resolution in living cells. PARIS analysis in three human and mouse cell types reveals frequent long-range structures, higher-order architectures, and RNA-RN...
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ژورنال
عنوان ژورنال: Cell
سال: 2016
ISSN: 0092-8674
DOI: 10.1016/j.cell.2016.04.028